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1

[RSC Drug Discovery] Designing Multi-Target Drugs || Chapter 1. Simple Drugs Do Not Cure Complex Diseases: The Need for Multi-Targeted Drugs

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 240 KB

english, 2012

2

Asymmetric nucleophilic fluorination under hydrogen bonding phase-transfer catalysis

Pupo, Gabriele, Ibba, Francesco, Ascough, David M. H., Vicini, Anna Chiara, Ricci, Paolo, Christensen, Kirsten E., Pfeifer, Lukas, Morphy, John Richard, Brown, John M., Paton, Robert S., Gouverneur, V

Journal:

Year:

2018

Language:

english

File:

PDF, 861 KB

english, 2018

3

Potent and selective inhibitors of gelatinase-A 2. carboxylic and phosphonic acid derivatives

J.Richard Morphy, Nigel R.A. Beeley, Byron A. Boyce, Joanna Leonard, Barbara Mason, Andrew Millican, Kenneth Millar, James P. O'Connell, John Porter

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 348 KB

english, 1994

4

Potent and selective inhibitors of gelatinase-a 1. hydroxamic acid derivatives

John R. Porter, Nigel R.A. Beeley, Byron A. Boyce, Barbara Mason, Andrew Millican, Kenneth Millar, Joanna Leonard, J.Richard Morphy, James P. O'Connell

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 341 KB

english, 1994

5

Conversion of highly malignant colon cancer from an aggressive to a controlled disease by oral administration of a metalloproteinase inhibitor

Zili An, Xiaoen Wang, Neville Willmott, Surinder K. Chander, Simon Tickle, Andrew J. P. Docherty, Andrew Mountain, Andrew T. Millican, Richard Morphy, John R. Porter, R. Ola Epemolu, Tetsuro Kubota, A

Journal:

Clinical and Experimental Metastasis

Year:

1997

Language:

english

File:

PDF, 953 KB

english, 1997

6

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 810 || Chapter 2. Clinical Need and Rationale for Multi-Target Drugs in Psychiatry

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 430 KB

english, 2012

7

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 810 || Chapter 4. Chemoinformatic Approaches to Target Identification

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 558 KB

english, 2012

8

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 5b || Chapter 8. Historical Strategies for Lead Generation

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 772 KB

english, 2012

9

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 104 || Chapter 3. Drug Molecules and Biology: Network and Systems Aspects

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 471 KB

english, 2012

10

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 810 || Chapter 5. Designing Multi-Target Drugs: In Vitro Panel Screening – Biological Fingerprinting

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 1.03 MB

english, 2012

11

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 5b || Chapter 9. In Silico Lead Generation Approaches in Multi-Target Drug Discovery

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 680 KB

english, 2012

12

Circulation: Cardiovascular Interventions Editors' Picks: Most Important Articles Published in 2011

Morphy, J. Richard, Harris, C John

Journal:

Year:

2012

Language:

english

File:

PDF, 336 KB

english, 2012

13

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 654 || Chapter 14. Discovery of HDAC-Inhibiting Multi-Target Inhibitors

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 1.03 MB

english, 2012

14

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 5b || Chapter 7. Target/s Identification Approaches – Experimental Biological Approaches

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 675 KB

english, 2012

15

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 810 || Chapter 10. The Challenges of Multi-Target Lead Optimization

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 478 KB

english, 2012

16

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 810 || Chapter 11. Combination Agents Versus Multi-Targeted Agents – Pros and Cons

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 333 KB

english, 2012

17

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 578 || Chapter 12. The Discovery of Lapatinib

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 1.55 MB

english, 2012

18

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 654 || Epilogue

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 155 KB

english, 2012

19

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 654 || Chapter 15. Targeting Protein–Protein Interactions: Dual Inhibitors of Bcl-2 and Bcl-xL

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 2.23 MB

english, 2012

20

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 654 || Chapter 13. Identification and Optimization of Dual PI3K/mTOR Inhibitors

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 671 KB

english, 2012

21

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 654 || Chapter 19. Designing Drugs with Dual Activity: Novel Dual Angiotensin II and Endothelin Receptor Antagonists

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 1.26 MB

english, 2012

22

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 654 || Chapter 17. The Rational Design of Triple Reuptake Inhibitors for the Treatment of Depression

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 1.71 MB

english, 2012

23

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 654 || Subject Index

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 168 KB

english, 2012

24

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 654 || Chapter 20. Ethyl Urea Inhibitors of the Bacterial Type II Topoisomerases DNA Gyrase (GyrB) and Topoisomerase IV (ParE)

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 853 KB

english, 2012

25

[RSC Drug Discovery] Designing Multi-Target Drugs Volume 93 ||

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 155 KB

english, 2012

26

[RSC Drug Discovery] Designing Multi-Target Drugs || Chapter 6. Phenotypic and In Vivo Screening: Lead Discovery and Drug Repurposing

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 180 KB

english, 2012

27

[RSC Drug Discovery] Designing Multi-Target Drugs || Introduction

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 158 KB

english, 2012

28

[RSC Drug Discovery] Designing Multi-Target Drugs || Chapter 18. Discovery of Multi-Target Agents for Neurological Diseases via Ligand Design

Morphy, J. Richard, Harris, C John

Year:

2012

Language:

english

File:

PDF, 644 KB

english, 2012

29

Solid Phase Synthesis of Tertiary Amines on Amide REM Resins: Grignard and Metal Hydride Compatible Resins

Plater, M. John, Murdoch, Alison M., Morphy, J. Richard, Rankovic, Zoran, Rees, David C.

Journal:

Journal of Combinatorial Chemistry

Year:

2000

Language:

english

File:

PDF, 101 KB

english, 2000

30

The Dual Role of Thiourea in the Thiotrifluoromethylation of Alkenes

Ricci, Paolo, Khotavivattana, Tanatorn, Pfeifer, Lukas, Medebielle, Maurice, Morphy, John Richard, Gouverneur, Veronique

Journal:

Chemical Science

Year:

2016

Language:

english

File:

PDF, 724 KB

english, 2016

31

Review Oncologic, Endocrine & Metabolic: Recent developments in matrix metalloproteinase inhibitors

Porter, John R, Millican, T Andrew, Morphy, J Richard

Journal:

Expert Opinion on Therapeutic Patents

Year:

1995

Language:

english

File:

PDF, 848 KB

english, 1995